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Troubled HCL loses another board member

first_img Read This NextRicky Schroder Calls Foo Fighters’ Dave Grohl ‘Ignorant Punk’ forThe WrapCNN’s Brian Stelter Draws Criticism for Asking Jen Psaki: ‘What Does theThe WrapDid Donald Trump Wear His Pants Backwards? Kriss Kross Memes Have AlreadyThe WrapPink Floyd’s Roger Waters Denies Zuckerberg’s Request to Use Song in Ad:The WrapHarvey Weinstein to Be Extradited to California to Face Sexual AssaultThe Wrap2 HFPA Members Resign Citing a Culture of ‘Corruption and Verbal Abuse’The Wrap’Black Widow’ First Reactions: ‘This Is Like the MCU’s Bond Movie’The Wrap’The View’: Meghan McCain Calls VP Kamala Harris a ‘Moron’ for BorderThe WrapKatt Williams Explains Why He Believes There ‘Is No Cancel Culture’ inThe Wrap Tuesday 1 March 2011 8:30 pm CRISIS-HIT medical recruiter Healthcare Locums lost another director yesterday, after its chief operating officer Mo Dedat stepped down from the board with immediate effect. HCL, whose shares remain suspended from AIM pending an internal probe into accounting problems, now has four directors including suspended chief financial officer Diane Jervis. Chairman Peter Sullivan, who joined the firm last month, said Dedat will continue to work for the company but has left the board to help “introduce new and independent talent”. The company refused to say whether or when new directors will be appointed. “There are no strict rules for AIM companies’ corporate governance, but you would expect as a minimum a chief executive and a chief financial officer, and a balance of non-executives,” Philip Quigley, head of transaction services at Smith & Williamson, told City A.M.. An investigation into HCL’s accounts is due to report its findings “in a matter of weeks”. The firm’s founder Kate Bleasdale was suspended and stepped down two weeks ago, followed by several other board members amid a shareholder rebellion. whatsapp KCS-content Share Show Comments ▼center_img Troubled HCL loses another board member Ad Unmute by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeMisterStoryWoman Files For Divorce After Seeing This Photo – Can You See Why?MisterStoryUndoMoneyPailShe Was A Star, Now She Works In ScottsdaleMoneyPailUndoTotal PastThe Ingenious Reason There Are No Mosquitoes At Disney WorldTotal PastUndoPeople TodayNewborn’s Strange Behavior Troubles Mom, 40 Years Later She Finds The Reason Behind ItPeople TodayUndoSerendipity TimesInside Coco Chanel’s Eerily Abandoned Mansion Frozen In TimeSerendipity TimesUndoBrake For ItThe Most Worthless Cars Ever MadeBrake For ItUndoBetterBe20 Stunning Female AthletesBetterBeUndoElite HeraldExperts Discover Girl Born From Two Different SpeciesElite HeraldUndoautooverload.comDeclassified Vietnam War Photos The Public Wasn’t Meant To Seeautooverload.comUndo whatsapp Tags: NULLlast_img read more

Kenya Commercial Bank Limited (KCB.tz) Q12014 Interim Report

first_imgKenya Commercial Bank Limited (KCB.tz) listed on the Dar es Salaam Stock Exchange under the Banking sector has released it’s 2014 interim results for the first quarter.For more information about Kenya Commercial Bank Limited (KCB.tz) reports, abridged reports, interim earnings results and earnings presentations, visit the Kenya Commercial Bank Limited (KCB.tz) company page on AfricanFinancials.Document: Kenya Commercial Bank Limited (KCB.tz)  2014 interim results for the first quarter.Company ProfileKenya Commercial Bank Limited is a leading financial institution in Tanzania offering retail and corporate banking services as well as mortgages, treasury and Bancassurance services. Kenya Commercial Bank offers financial solutions ranging from current accounts, overdrafts and loans to fixed and short-term deposits, mortgage finance, trade finance and forex, and business investment accounts. The banking institution participates in investments in Treasury Bills and Bonds with the central banks. Wholly-owned subsidiaries in the banking group include Kenya Commercial Finance Company Limited, Savings & Loan Kenya Limited, Kenya Commercial Bank Nominees Limited, Kencom House Limited, KCB Tanzania Limited, KCB Sudan Limited, KCB Rwanda SA and KCB Uganda Limited. Kenya Commercial Bank Limited is listed on the Dar es Salaam Stock Exchange.last_img read more

Saints and Sinners: The weekend’s talking points

first_imgFine finishesThere was plenty for Sale to be happy about in their 34-30 win over Leicester Tigers as they took advantage of some porous defence by the visitors and scored four tries. Mike Phillips got the ball rolling with a fine individual effort, then teenage wing Paolo Odogwu sprinted over after Josh Beaumont had taken possession at the back of a lineout.However the try of this Aviva Premiership match was scored by Leicester wing Adam Thompstone. Receiving the ball on the right, he was tackled by Odogwu from one side and Byron McGuigan from the other but somehow, as they dragged him into touch in the corner, he reached his arm between their bodies and touched the ball down. With Leicester trailing 31-23 at the time, even after Owen Williams’ excellent conversion it wasn’t enough to snatch the win for the Tigers, but the try did at least earn them a losing bonus point. TAGS: Wasps Double troubleReferee Dudley Phillips joins the players in the doghouse this week after awarding a try to Leinster despite a clear double-movement from scorer Rhys Ruddock – and as the match ended up as a 16-13 win for the Irish side against Cardiff Blues, it was a crucial mistake.Ruddock was dragged up to the line but clearly grounded the ball short to start with then, a couple of seconds later, moved it forward. Phillips opted not to use the television match official, but if he had done the try would surely have been disallowed.Josh Navidi did the Blues no favours when he conceded the penalty which ultimately gave Leinster their win. Running back from an offside position he got in the way of a pass by scrum-half Jamison Gibson-Park. It was cute play by the number nine but Navidi shouldn’t have been there. The SaintsYoung and giftedSeven tries from seven different scorers and a 47-18 win over Harlequins – be in no doubt, Wasps are the team to watch at the moment.It is impossible to pick out individual Saints from among the Wasps players after their fifth win from five Aviva Premiership matches this season, so instead it is hats off to their boss Dai Young. He has put together a multi-talented squad and got them playing stunning rugby. Next weekend their title credentials will get the sternest of tests at they travel to take on champions Saracens, but Wasps will go into the match on a hot streak of form with nothing to fear and Saracens will be wary of being stung.Munster also scored seven tries this weekend, with CJ Stander grabbing two, as they cruised to a 49-5 win over Zebre in the Guinness Pro12. Glasgow were trailing 17-16 when Allan received the ball outside the 22. He looked up, saw a hint of a gap between two forwards, dummied, stepped and broke the line and from there it was a straight run and slide over the whitewash. One to treasure for the prop, and one which won’t need exaggerating when he re-tells the story in months to come! The SinnersLeaky LeicesterLeicester‘s loss at Sale Sharks was the third time this season they have conceded more than 30 points. This time the main problem seemed to be around the breakdown, as first they left a gap for Mike Phillips to charge through to open the scoring, then Johnny Leota smashed through on the half-hour before Halani ’Aulika barged his way over the line to give Sale a decent lead going into the last quarter. Richard Cockerill will be demanding an improvement from Leicester when they host Worcester next weekend. Payne’s effort not in vain Jared Payne helped Ulster scrape to a 9-7 home win over the Ospreys with a critical try-saving tackle on Eli Walker and in doing so enabled his team to maintain their 100% start to the season in the Guinness Pro12.The Welsh wing chased a kick from Rhys Webb up the left wing and beat Payne to the bouncing ball, but the Ulster centre didn’t panic and he brought Walker down, then spun around as he slid along the turf and forced Walker away from the try-line and into touch.Ulster were trailing 7-6 at the time so if Walker had scored, the Welsh side might have gone on to see out the game. As it was, Ulster forced a last-minute penalty and Paddy Jackson kicked it to steal the victory for the home side. LATEST RUGBY WORLD MAGAZINE SUBSCRIPTION DEALScenter_img The Young One: Wasps fans have a lot to thank Dai Young for. (Photo: Getty Images) North and Picamoles get the Saints marchingNorthampton went in to Friday’s match against Exeter Chiefs searching for their first home win of the season and managed to scrape by 20-19 thanks to some heroics from several players.It didn’t look very promising for the Saints when they were trailing 13-0 in the first half, but Louis Picamoles – who had a terrific game – powered into the Chiefs’ 22 and helped create the chance for George North to power over in the corner.Just a minute later, North caught the re-start kick deep in his own 22 and set off on a swerving run, cutting inside then out and making 50 metres of ground before passing to Nic Groom, who shipped the ball on to Rory Hutchinson to score a try on debut.Roar for Rory: Northampton’s replacements are pleased with Hutchinson’s try. (Photo: Getty Images)The young centre hadn’t even been expecting to play and was only in the side because Harry Mallinder had to move from centre to fly-half to replace Stephen Myler on the eve of the game. And Mallinder played a key role as he stepped up and kicked a penalty when Northampton were trailing 19-17 with two minutes of the match remaining.Picamoles, whose breaks and offloads had been mesmerising throughout the game, had the final say, booting the ball into touch when the clock had gone red to secure the narrowest of wins. Thanks, but no thanks Sinoti Sinoti might owe Dominic Waldouck a pint when his foolish and low long pass left the centre stooping to collect the ball and the on-rushing Jackson Willison in the same instant. Willison claimed the ball and both he and Waldouck were left in a heap on the floor as Tom Heathcote took it on and raced towards the line, then put Wynand Olivier in for the try. That gave Worcester Warriors a 5-0 lead and they went on to beat Newcastle 11-9 and claim their first Premiership win since March.Try time: Anthony Watson heads for home with Burns in his wake. (Photo: Getty Images)Inglorious GloucesterAlmost the entire Gloucester team could be Sinners this week after their third home defeat of the season, at turgid 15-6 loss West Country rivals Bath. They were errors all over the place but the game turned on a lost lineout midway through the second half. Gloucester were 6-3 up and had just repelled a sustained Bath attack, earning a penalty with which to clear their lines. However, from the lineout on halfway they lost possession and Bath put them back under pressure and created the decisive try for Anthony Watson from there, with the wing brushing off a tackle from Billy Burns too easily.Late in the game Gloucester had the chance to at least snatch a losing bonus point from a dire match but when they were awarded a kickable penalty Willi Heinz foolishly decided to tap and go, in search of a try which would not, by then, have been enough to win the game. Gloucester could not cross the whitewash and were left to rue their many errors. In full flight: Alex Allan on his way to the try-line at Rodney Parade. (Photo: Huw Evans Agency)A try to treasureProps just love to score tries from 25-metre breaks, with a jink or a side-step to take them past the grasping hands of beaten defenders. Unfortunately, this rarely happens, and the big men wearing the small numbers are more likely to flop over the line from two paces.However, Glasgow Warriors’ No 1 Alex Allan scored a try to be proud of on Friday and helped his team beat the Newport Gwent Dragons 26-17 at Rodney Parade. Some stunning games lit up round five of the Aviva Premiership and Guinness Pro12 seasons, but there were some turgid tussles as well. New look: Palma-Newport’s beard and its tiny pigtail. (Photo: Getty Images)Weird beardEver met a man with a pigtail in his beard? Bath prop Kane Palma-Newport has decided the way to tame his copious facial hair is to capture some of it in a tiny pony-tail. However, it doesn’t really make much difference to the volume of his beard and, as the BT Sport commentators said during Saturday’s match at Gloucester, it is just asking to be pulled.last_img read more

Disciplinary action to follow after U19 player loses and uses his head AFTER red cards

first_imgWednesday Oct 3, 2018 Disciplinary action to follow after U19 player loses and uses his head AFTER red cards The Western Province rugby union has confirmed that they are looking into the nasty incident that saw two players involved in an ugly brawl after they were red carded in an U19 match.ADVERTISEMENTTwo outside backs got in a scuffle after Eastern Province under-19 fullback Dylan le Roux made a legal try-saving tackle on Western Province under-19 winger, Christian Ambadiang.The Cameroon-born winger appeared to lash out at le Roux before the two got in a scuffle as le Roux held his leg. Ambadiang then pushed le Roux and le Roux punched him, dropping him momentarily.Once everything had settled down, the referee sent both players from the field, but the nastiness wasn’t over as Ambadiang then headbutted le Roux, causing another big ruckus.WP went on to win the match 48-17 but the fall out has been large, with footage being shared far and wide on social media.The Western Province rugby union has promised to take action after an investigation into the incident.“We’ll follow the correct procedures. As the match falls under the auspices of the SA Rugby Union, there is a disciplinary process that WP and the player will follow,” said a WP spokesman. “We take foul play and violent behaviour very seriously and an internal disciplinary process will also take place at WP.”ADVERTISEMENTLonger clip below (with some possible audio issues) Posted By: rugbydump Share Send Thanks Sorry there has been an error Big Hits & Dirty Play , See it to Believe it Related Articles 25 WEEKS AGO Suspensions handed down after testicle grabbing… 26 WEEKS AGO The ‘double ruffle’ splits opinion with fans… 26 WEEKS AGO WATCH: The nastiest and most brutal moments… From the WebThis Video Will Soon Be Banned. Watch Before It’s DeletedSecrets RevealedYou Won’t Believe What the World’s Most Beautiful Girl Looks Like TodayNueeyUrologists Stunned: Forget the Blue Pill, This “Fixes” Your EDSmart Life ReportsGranny Stuns Doctors by Removing Her Wrinkles with This Inexpensive TipSmart Life ReportsIf You Have Ringing Ears Do This Immediately (Ends Tinnitus)Healthier Living30+ Everyday Items with a Secret Hidden PurposeNueeyThe content you see here is paid for by the advertiser or content provider whose link you click on, and is recommended to you by Revcontent. As the leading platform for native advertising and content recommendation, Revcontent uses interest based targeting to select content that we think will be of particular interest to you. We encourage you to view your opt out options in Revcontent’s Privacy PolicyWant your content to appear on sites like this?Increase Your Engagement Now!Want to report this publisher’s content as misinformation?Submit a ReportGot it, thanks!Remove Content Link?Please choose a reason below:Fake NewsMisleadingNot InterestedOffensiveRepetitiveSubmitCancellast_img read more

Hinanai Village House / DYGSA

first_imgArchDaily Photographs:  Courtesy of DYGSA Photographs “COPY” ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/484832/hinanai-village-house-dygsa Clipboard 2013 Projects ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/484832/hinanai-village-house-dygsa Clipboard Architects: DYGSA Area Area of this architecture project CopyHouses•Hiroshima, Japan Collaborators:Koura ArchitectsCity:HiroshimaCountry:JapanMore SpecsLess Specs Save this picture!Courtesy of DYGSAText description provided by the architects. The house is ideally suited for the client’s family of four – parents and two kids – with the purpose of spending weekends in the natural environment. It is situated on the top of a hill with the spectacular view over the surrounding area. The one-story house is in the shape of a square with sides that are 9.5m long. It stands on the front edge of the lot of about 2000㎡, so the facade of the house shuts out the sight of the garden from the side of the road.Save this picture!Courtesy of DYGSAThe main partition wall meets the ends at angles 80 and 100 degrees, which widens the view from the inside into the outside and raises awareness about the natural surroundings. The path made of concrete and leading to the front wooden sliding door stretches to the inside space and reaches the glass sliding doors on the opposite side of the house.So when you open the front door, you get the feeling as if the inside space is the continuation of the outside one, and that makes it possible to bring the outdoor activities inside. The line of the inside concrete path focuses on the old red pine tree in the garden.Save this picture!Floor PlanThus, the glass doors’ frame acts as a picture frame with the natural landscape in it. Moreover, on opening the inside sliding doors separating the wooden floor space and the concrete floor space, you get one spacious room. In this way the ordinary and extraordinary activities blend in one splendid hybrid space.Save this picture!Courtesy of DYGSAProject gallerySee allShow lessNew Shelter in Ruavieja / Sergio RojoSelected ProjectsTall Tinder: Are Wooden Skyscrapers Really Fire Safe?Articles Share Year:  Save this picture!Courtesy of DYGSA+ 20 Share Japan “COPY” Contractor: Area:  91 m² Area:  91 m² Year Completion year of this architecture project Houses Hinanai Village House / DYGSASave this projectSaveHinanai Village House / DYGSA Fuji Construction Hinanai Village House / DYGSA Year:  2013 CopyAbout this officeDYGSAOfficeFollowProductsWoodConcrete#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesHiroshimaHousesJapanPublished on March 11, 2014Cite: “Hinanai Village House / DYGSA” 11 Mar 2014. ArchDaily. Accessed 11 Jun 2021. ISSN 0719-8884Browse the CatalogMetal PanelsAurubisCopper Alloy: Nordic BrassCompositesMitrexPhotovoltaic Solar Cladding – BIPV CladdingPanels / Prefabricated AssembliesTechnowoodPanel Façade SystemArmchairsUniForArmchair – ParigiLouvers / ShuttersBruagShading Screens – Perforated Facade PanelsAluminium CompositesSculptformAluminium Façade BladesCultural / PatrimonialIsland Exterior FabricatorsSeptember 11th Memorial Museum Envelope SystemWire MeshJakobWebnet in a Gymnasium in GurmelsDoorsLinvisibileLinvisibile Pocket Door | MareaPaintKEIMMineral Paint for Concrete – KEIM Concretal®-WLouversReynaers AluminiumSolar ShadingHandlesFormaniFitting Collection – ARCMore products »Save世界上最受欢迎的建筑网站现已推出你的母语版本!想浏览ArchDaily中国吗?是否翻译成中文现有为你所在地区特制的网站?想浏览ArchDaily中国吗?Take me there »✖You’ve started following your first account!Did you know?You’ll now receive updates based on what you follow! Personalize your stream and start following your favorite authors, offices and users.Go to my streamlast_img read more

Readership figures

Find out more about FundUK from UK Fundraising. About Howard Lake Howard Lake is a digital fundraising entrepreneur. Publisher of UK Fundraising, the world’s first web resource for professional fundraisers, since 1994. Trainer and consultant in digital fundraising. Founder of Fundraising Camp and co-founder of GoodJobs.org.uk. Researching massive growth in giving. AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis Not sure in which newspaper to advertise? Visit The ADWEB UK Regional Newspaper Database Service to search the readership database of the Newspaper Society and JICREG’s figures on the demographic coverage of local radio stations.Not sure in which newspaper to advertise? Visit Service The ADWEB UK Regional Newspaper Database to search the readership database of the Newspaper Society and JICREG’s figures on the demographic coverage of local radio stations.This useful resource was suggested by Nigel Parkes of the Shaw Trust in a message to FundUK ,the e-mail discussion list for UK fundraisers. Advertisement Readership figures  83 total views,  1 views today AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to LinkedInLinkedInShare to EmailEmailShare to WhatsAppWhatsAppShare to MessengerMessengerShare to MoreAddThis Howard Lake | 17 January 2000 | News read more

Bistro Burnett shifts to Grubhub pickup only

first_imgFacebook World Oceans Day shines spotlight on marine plastic pollution Asia Soliday Twitter ReddIt Linkedin Previous articleEmergency drills in buildings cut short due to social distancingNext articleTarrant County Elections administrator details Election Day during COVID-19 Asia Soliday RELATED ARTICLESMORE FROM AUTHOR Asia Solidayhttps://www.tcu360.com/author/asia-soliday/ printThis semester, Bistro Burnett, the only dining option in the Mary Couts Burnett Library, is exclusively accepting online orders as a COVID-19 precaution.In a normal semester, the cafe in a corner of the library would be crowded with long lines in limited space. But these lines aren’t forming this year, because the only way to get a sandwich at Bistro Burnett is to order through the Grubhub app. Other dining options on campus, such as Chick-fil-A and Union Grounds, are still taking in-person orders. None of TCU’s other on-campus dining options, such as Chick-fil-A and Union Grounds, have had to make the same switch, but the bistro’s limited space usually creates long lines that do not allow for social distancing.  “It’s frustrating because I’ll walk into the library and want a water bottle but I know I have to order on Grubhub then sit there and wait for 5 minutes.”Junior finance major Anna HylandPrior to the beginning of the school year, the Dining Services team came to the conclusion that it would be impossible for students to follow social distancing guidelines if Bistro Burnett were ever to reach maximum capacity. To address this, the team spent time measuring and pre-marking 6-foot distances in all dining areas where lines form. Students continue to enjoy study snacks from Bistro Burnett while hard at work in the library. (Heesoo Yang/Staff Photographer)Dining Services’ Swati Bharathi said, “I thought [the transition] was going to be a lot harder, but honestly I think that what helped was everyone — including our employees, management and staff — have all used Grubhub on our own time. Because [Grubhub] was already in place at a national level, regardless of where you were coming from in the country, when [students] came here they knew it was nothing different.”Students can use Campus Cash to order from Bistro Burnett on Grubhub. Some of them have experienced difficulties involving the Grubhub app, but many have found that their issues are easily fixed by changing their locations from their hometowns to Fort Worth.“There have been very simple solutions, and because a lot of classes have gone online, campus has been very quiet and I think that also helps with the lines,” said Bharathi. “We’re here and we’re ready to go if there are changes that need to be made. We’ve had our management team out there constantly talking to students.”  Asia Solidayhttps://www.tcu360.com/author/asia-soliday/ Asia Solidayhttps://www.tcu360.com/author/asia-soliday/ Twitter TCU News Now 4/28/2021center_img TCU places second in the National Student Advertising Competition, the highest in school history What we’re reading: Presidential debate full of insults, murder-suicide in Fort Worth + posts Facebook Linkedin ReddIt Riff Ram Vintage holds pop-up at Common Grounds The bistro is located in the Mary Couts Burnett Library on TCU’s campus. (Heesoo Yang/Staff Photographer) Welcome TCU Class of 2025 Milton Daniel residents engage in friendly competition Asia Solidayhttps://www.tcu360.com/author/asia-soliday/last_img read more

Positive BNC210 7-Day Dosing Pharmacokinetic Study Exceeds Blood Exposure Projected for Phase 2b PTSD…

first_img Twitter Pinterest Previous articleIn Israel and beyond, virus vaccines bring political powerNext articleJuniper Research: Smart Traffic Management to Significantly Reduce Congestion and Emissions; Saving Cities $277 Billion by 2025 Digital AIM Web Support BNC210 novel oral tablet formulation (900 mg given twice daily) exceeds blood exposure projected for upcoming Phase 2b PTSD trialBNC210 Phase 2b PTSD trial on target for start in mid-2021 with final dose selected ADELAIDE, Australia, Feb. 22, 2021 /PRNewswire/ — Bionomics Limited (ASX: BNO, OTCQB: BNOEF, Germany: AU000000BNO5), a global, clinical stage biopharmaceutical company, today announced positive pharmacokinetic (PK) results from a 7-day dosing study in healthy volunteers using the newly developed solid dose oral tablet formulation of BNC210. BNC210 is a novel, negative allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in development for the treatment of anxiety and stressor-related disorders, and in November 2019 was granted Fast Track designation by the US Food and Drug Administration (FDA) for the treatment of Post-Traumatic Stress Disorder (PTSD). The 7-day dosing PK study in ten healthy volunteers (females and males) demonstrated that at a dose of 900 mg given twice daily, the tablet formulation of BNC210 had steady-state 12-hourly exposure levels ranging from 33-57 mg.h/L which exceed the 12-hourly blood exposure of ~25 mg.h/L predicted as necessary to meet the primary endpoints for effectiveness for treating PTSD patients in future clinical trials. A pharmacometric analysis of data from the first Phase 2 PTSD trial (RESTORE) that read out in October 2018, modelled an exposure-response relationship between BNC210 blood levels and CAPS-5 scores (the primary endpoint measure in PTSD trials), and the potential for BNC210 to treat PTSD symptoms provided that adequate blood exposure could be achieved. The tablet formulation of BNC210 replaces the liquid suspension formulation used in RESTORE which did not provide sufficient blood exposure for efficacy in that Study. The BNC210 tablet will be easier for the PTSD trial participants to administer and, unlike the liquid suspension formulation, is not dependent on food intake for maximal absorption and is therefore expected to result in substantially less variable exposure in the patients in the next Phase 2b PTSD study. Furthermore, the recent PK results show that there is no gender-based difference in exposure and that BNC210 continues to be well-tolerated, even at the higher exposure levels achieved after 7 days of dosing in the healthy volunteers. Dr. Errol De Souza, Executive Chairman of Bionomics said, “We are extremely pleased with the results of the 7-day PK study which demonstrate that we reach steady-state levels on the second day following the start of twice daily dosing and that we not only meet but exceed the blood exposure predicted from the pharmacometric analysis as necessary for future trials. With the dose now selected, we can initiate manufacturing of the tablets, clinical site selection and regulatory filings in preparation for a Phase 2b trial with BNC210 in PTSD patients projected for mid-2021. The recently oversubscribed Private Placement of approximately $16 million along with the proposed Entitlement Offer to our current shareholders will provide us with the funds necessary for BNC210 development.” AUTHORISED BY THE BOARD OF DIRECTORS About Bionomics Limited Bionomics (ASX: BNO, OTCQB: BNOEF, Germany: AU000000BNO5) is a global, clinical stage biopharmaceutical company leveraging its proprietary platform technologies to discover and develop a deep pipeline of best in class, novel drug candidates. Bionomics’ lead drug candidate BNC210, currently in development for initiation of a second Phase 2 trial for the treatment of PTSD, is a novel, proprietary negative allosteric modulator of the alpha-7 nicotinic acetylcholine receptor. Beyond BNC210, Bionomics has a strategic partnership with Merck & Co., Inc (known as MSD outside the United States and Canada) with two drugs in early stage clinical trials for the treatment of cognitive deficits in Alzheimer’s disease. www.bionomics.com.au Factors Affecting Future Performance This announcement contains “forward-looking” statements within the meaning of the United States’ Private Securities Litigation Reform Act of 1995. Any statements contained in this announcement that relate to prospective events or developments, including, without limitation, statements made regarding Bionomics’ drug candidates (including BNC210), its licensing agreements with Merck & Co. and any milestone or royalty payments thereunder, drug discovery programs, ongoing and future clinical trials, and timing of the receipt of clinical data for our drug candidates are deemed to be forward-looking statements. Words such as “believes,” “anticipates,” “plans,” “expects,” “projects,” “forecasts,” “will” and similar expressions are intended to identify forward-looking statements. There are a number of important factors that could cause actual results or events to differ materially from those indicated by these forward-looking statements, including unexpected safety or efficacy data, unexpected side effects observed in clinical trials, risks related to our available funds or existing funding arrangements, our failure to introduce new drug candidates or platform technologies or obtain regulatory approvals in a timely manner or at all, regulatory changes, inability to protect our intellectual property, risks related to our international operations, our inability to integrate acquired businesses and technologies into our existing business and to our competitive advantage, as well as other factors. Results of studies performed on our drug candidates and competitors’ drugs and drug candidates may vary from those reported when tested in different settings. View original content: http://www.prnewswire.com/news-releases/positive-bnc210-7-day-dosing-pharmacokinetic-study-exceeds-blood-exposure-projected-for-phase-2b-ptsd-trial-301232333.html SOURCE Bionomics LimitedCopyright © 2021 PR Newswire Association LLC. All Rights Reserved. Facebook Positive BNC210 7-Day Dosing Pharmacokinetic Study Exceeds Blood Exposure Projected for Phase 2b PTSD Trial WhatsApp Local NewsBusinesscenter_img TAGS  Pinterest Twitter By Digital AIM Web Support – February 22, 2021 Facebook WhatsApplast_img read more

Shots fired in Dungiven overnight

first_img News, Sport and Obituaries on Monday May 24th WhatsApp Arranmore progress and potential flagged as population grows Twitter Facebook Google+ By News Highland – December 14, 2020 Homepage BannerNews Pinterest Facebook WhatsApp Shots fired in Dungiven overnightcenter_img Pinterest Shots were last night fired at a house in Dungiven.It was reported that shots were fired at the front door of the house at around 10.10 pm.Police say that there have been no reports of any injuries as a result of this incident.There are no further details at this time. DL Debate – 24/05/21 Important message for people attending LUH’s INR clinic RELATED ARTICLESMORE FROM AUTHOR Previous article429 new cases confirmed this evening, 46 in DonegalNext articleMajority of people continue to buy from local businesses News Highland Twitter Loganair’s new Derry – Liverpool air service takes off from CODA Google+ Harps come back to win in Waterford last_img read more

Six confirmed dead after midair plane crash over Alaska

first_imgRetired_Tim/iStock(ANCHORAGE, Alaska) — Six people died and 10 others were hospitalized after two aircraft collided in midair over Alaska on Monday, according to the U.S. Coast Guard.Alaska State Troopers confirmed the identities of the deceased after notifying their next of kin. They are:Simon Bodie, 56, of Tempe, New South Wales, AustraliaLouis Both, 46, San DiegoRandy Sullivan, 46, of Ketchikan, Alaska, one of the aircraft’s pilotsCassandra Webb, 62, of St. LouisElsa Wilk, 37, of Richmond, British Columbia, CanadaRuan Wilk, 39, of UtahThe Canadian and Australian consulates have been notified, according to state troopers.As of early Tuesday, the search was ongoing for two travelers after four bodies had been recovered following the incident.“There are two people that we’re still searching for at this time,” Coast Guard Petty Officer Jon-Paul Rios told ABC News in an interview that aired Tuesday on Good Morning America. “Our crews are out there searching diligently alongside our partner agencies and some good Samaritans. They’ve been searching throughout the day, by both air and by sea.”The deadly collision took place Monday afternoon in Coon Cove, Alaska, according to the Federal Aviation Administration. A de Havilland DHC-2 Beaver with five people on board and a de-Havilland Otter DHC-3 carrying 11 people clashed in midair “under unknown circumstances,” the FAA said in a statement Monday.Ten people with injuries from the incident were taken to PeaceHealth Ketchikan Medical Center, according to hospital spokeswoman Mischa Chernick. Three of the patients were listed in serious condition, while seven were in fair condition, Chernick told ABC News.Both planes were on sightseeing tours, carrying guests from the Royal Princess cruise ship, which is on a seven-day voyage that departed Vancouver on May 11 and is scheduled to arrive in Anchorage on Saturday, according to Princess Cruise Lines.The aircraft collided approximately eight nautical miles from Ketchikan, Alaska.The two people who had been listed as missing, the Australian and the Canadian travelers, both were guests on the Royal Princess cruise ship, which has since departed the area and continued on its voyage, according to Princess Cruise Lines.“All of us at Princess Cruises are deeply saddened by this tragic news and we are extending our full support to the investigating authorities as well as the traveling companions of the guests involved,” Brian O’Connor, a spokesman for the cruise line, said in a statement Tuesday. “We immediately activated our Princess Care Team employees in the region and sent additional team members to Ketchikan overnight to assist the families impacted.”One of the planes was operated by Taquan Air, which said it has suspended all scheduled flights and is cooperating fully with investigators.“We are devastated by this news and our hearts go out to our passengers and their families,” the airline said in a statement Monday.The Coast Guard, the FAA and the National Transportation Safety Board are all investigating the incident.Copyright © 2019, ABC Radio. All rights reserved.last_img read more