SANTIAGO, Chile — On a weeklong trip to Chile and Brazil, Harvard President Drew Faust has been meeting with government and academic leaders, reconnecting with Harvard alumni, and getting a firsthand look at the tangible benefits of Harvard research.In Chile, she visited an early childhood education program at a public school and participated in a symposium organized by Harvard faculty, government leaders, and the heads of nongovernmental organizations involved in reconstruction efforts from last year’s earthquake.Later in the week, she was exchanging ideas with leaders of Brazilian universities and meeting with local students who have studied with Harvard faculty or alongside Harvard students in Brazil.A high point of Faust’s agenda was a meeting with Chilean President Sebastián Piñera, A.M. ’75, Ph.D. ’76, who greeted her at La Moneda Palace, Chile’s equivalent of the White House, shortly before the current resident of the White House, President Barack Obama, J.D. ’91, arrived for a state visit to Chile.“Forty years ago, Mr. President,” Piñera said to Obama in his welcoming remarks at a state dinner held in Obama’s honor, “I had the privilege of studying for a doctoral degree in the same University where you and your wife studied law, Harvard University, whose president, Drew Faust, is with us today.”Faust and Piñera discussed Becas Chile, a scholarship program sponsored by the Chilean government that has enabled an increasing number of students from that country to study at Harvard. They also discussed the many ways in which Harvard is connected to Chile.Jorge Dominguez, vice provost for international affairs, attended the meeting, and noted later that three of Piñera’s cabinet ministers are Harvard alumni: Felipe Larraín, A.M. ’83, Ph.D. ’85, finance minister; Felipe Kast, Ph.D. ’09, planning and cooperation minister; and Felipe Bulnes, LL.M. ’96, minister of justice. “The president and the three Felipes exemplify one of the ways that Harvard’s relationship with Chile is long and productive,” said Dominguez.Faust and her husband, Charles Rosenberg, attended a state dinner held in Obama’s honor later that night. In his welcoming remarks, Piñera cited his Harvard connection with Obama and noted that Faust was a guest at the dinner.Since being chosen as the first woman to lead Harvard, Faust has made it a point to visit schools for girls when she travels abroad to talk about the importance of education and the opportunities it affords young women. At Liceo Carmela Carvajal, a public school for girls in Santiago, Faust made a surprise visit to an upstairs classroom before meeting with a group of 16 students, mostly seniors clad in blue school uniforms, who sat in a semicircle in a basement room and conversed with her in English.The students talked about relating to boys and the rapidly changing role of women in society. But mostly they were eager to share their aspirations with Faust.One young woman said she wanted to be a “great archaeologist,” while another dreamed of traveling the world and writing. Their classmates spoke of curing disease, of becoming a biotechnology researcher, a journalist, and an artist. “I want people to see the beauty of everything and everyone,” said the future painter.Faust offered a bit of advice that she shares with graduating Harvard seniors who are struggling with which paths to follow into the future. “I always say to them, follow your passion,” she said, “and if that doesn’t work out you can try something else.”The classroom of Liceo Carmela Carvajal was not the last one that Faust visited in Chile. At Escuela Basica Arturo Alessandri Palma, she sat in on a kindergarten class that participates in Un Buen Comienzo (UBC), a program modeled on the U.S. Head Start effort supported by the Fundación Educacional Oportunidad and the Chilean government. The program involves faculty from the Harvard Graduate School of Education, Harvard Medical School (HMS), and Harvard’s David Rockefeller Center for Latin American Studies.“The program aims to improve the children’s language and literacy skills, their social interactions, and to provide families with materials that strengthen the learning environment at home,” said Judith Palfrey of HMS. “UBC is based on the philosophy that education and health go hand in hand.”Harvard President Drew Faust (seated at left, black jacket) visits the kindergarten classroom of Maria Cristina Valenzuela (standing) at the Estación Central School, which uses the Un Buen Comienzo program. Un Buen Comienzo is modeled on the U.S. Head Start program.Before leaving Chile, Faust addressed a meeting of Harvard faculty and leaders from the government and nongovernmental groups that have been working together to help Chile recover from the February 2010 earthquake and tsunami that devastated large areas south of Santiago.The meeting, in which Harvard Kennedy School Dean David Ellwood and representatives from HMS and the Harvard Graduate School of Design also participated, was called to discuss how Harvard faculty could best contribute to the next phase of the recovery process, perhaps by helping to improve strategic long-term planning for emergency preparedness and assistance, and by marshaling people with expertise in public health, mental health, and design areas.“I have great admiration for the dedication and resilience you’ve shown as part of the reconstruction effort following last year’s earthquake and tsunami,” Faust told the audience. “And I’m proud that members of the Harvard community have invested their time and their expertise and their humane concern for others in helping Chile rebuild.”Faust also said, “I feel fortunate to be here today to help introduce the next stage of what had already been a strong and mutually beneficial partnership between Harvard and Chile. I share the hope that by working in close concert, we can better understand the public health and mental health issues arising from devastating natural disasters; that we can consider design solutions that will limit the damage done by future disasters; and that we can carry forward efforts on various fronts to advance the reconstruction efforts here in Chile.”Faust introduced Ellwood, who spoke about the importance of acting in time to respond to disasters — and preparing for them. One key for building consensus to plan for crises, he said, was forming partnerships and developing independent institutions that can validate preparedness and recovery efforts.Just as important, he said, is making a clear case for addressing potential problems. For example, the campaign to reduce the threat to the ozone layer was successful largely because images of it changing made a visual case for action.“If you see a problem and want to make a difference before and after, you have to make it vivid,” Ellwood said.
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Facebook Twitter Google+ The Daily Orange has worked to keep you covered on all the biggest news in Syracuse sports this year, from a major college football upset to an Atlantic Coast Conference record set on the hardwood.As the school year comes to a close, here’s our list of the five most newsworthy Syracuse sports stories of the 2017-18 academic year.Todd Michalek | Staff PhotographerOct. 13, 2017- Syracuse defeated then-No. 2 Clemson 27-24 inside the Carrier Dome for SU’s biggest upset since 1984. The Orange entered the game 24-point underdogs but stifled the defending national champions offense, holding the Tigers to just more than 200 yards passing. In front of 42,475 fans, SU’s largest crowd of the season, Orange head coach Dino Babers’ offense totaled 440 yards of offense and three touchdowns. In the game’s final frame, a Clemson fake punt ended its last possession while Eric Dungey extended SU’s final drive with a quarterback run.AdvertisementThis is placeholder textPaul Schlesinger | Staff PhotographerNov. 18, 2017- Justyn Knight, after coming up short for three consecutive years, finally captured an elusive National Championship in Louisville, Kentucky. It was the first accolade in a decorated season for the best runner in SU history.Codie Yan | Staff PhotographerFeb. 25, 2018- Tiana Mangakahia dished to Miranda Drummond for a 3 on the game’s first possession to set the ACC single-season assist record. Mangakahia hadn’t played collegiate basketball after sitting out two years at a community college. But the point guard from Australia took the country by storm in her first season at Syracuse. She tallied double-digit assists in her first eight games for SU. She picked up 14 double-doubles of points and assists on the season. She dropped 44 points against Georgia Tech on Jan. 4, and by the end of the season, she had 304 assists. Published on May 11, 2018 at 3:17 pm Alexandra Moreo | Senior Staff PhotographerMarch 14-23, 2018- After edging its way into the NCAA Tournament field, Syracuse beat Arizona State and TCU to advance to the Round of 32 and a date with Michigan State. Despite being the underdog in the matchup, the Orange narrowly bested the Spartans to keep their improbable run alive a year after missing the field altogether the year before. SU lost in the Sweet 16 to Duke.Hieu Nguyen | Staff PhotographerApril 1, 2018- Syracuse upset then-No. 3 Georgia Tech, 4-3. SU picked up the doubles point with a dominant, 6-2 win by Gabriela Knutson and Miranda Ramirez over the No. 1 doubles pair in the nation. Then, with Syracuse at three points and needing one to clinch, Knutson crushed an ace right down the middle of the court and past No. 22 Paige Hourigan. It was the biggest win, by ranking, in program history. Comments
ALAMEDA — Jordy Nelson was Jon Gruden’s big-name signing this offseason, the 33-year-old who supposedly still had the jets and hands to be an effective wide receiver in the NFL.Through two weeks – yes, it’s only two games – he’s yet to live up to that billing.While Jared Cook (nine catches for 180 yards in Week 1) and Amari Cooper (10 catches for 116 yards in Week 2) have already posted big games, Nelson has caught only five passes for 53 yards over two weeks. On Sunday alone, Nelson caught …
Ball-and-stick model of lincomycin. Credit: Jynto/Wikipedia Journal information: Nature Scientists study how marine bacteria release cloud-making compound Citation: Researchers unravel the elusive source of sulfur in an antibiotic (2015, January 15) retrieved 18 August 2019 from https://phys.org/news/2015-01-unravel-elusive-source-sulfur-antibiotic.html Explore further More information: Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A, Nature (2015) DOI: 10.1038/nature14137AbstractLow-molecular-mass thiols in organisms are well known for their redox-relevant role in protection against various endogenous and exogenous stresses1, 2, 3. In eukaryotes and Gram-negative bacteria, the primary thiol is glutathione (GSH), a cysteinyl-containing tripeptide. In contrast, mycothiol (MSH), a cysteinyl pseudo-disaccharide, is dominant in Gram-positive actinobacteria, including antibiotic-producing actinomycetes and pathogenic mycobacteria. MSH is equivalent to GSH, either as a cofactor or as a substrate, in numerous biochemical processes4, most of which have not been characterized, largely due to the dearth of information concerning MSH-dependent proteins. Actinomycetes are able to produce another thiol, ergothioneine (EGT), a histidine betaine derivative that is widely assimilated by plants and animals for variable physiological activities5. The involvement of EGT in enzymatic reactions, however, lacks any precedent. Here we report that the unprecedented coupling of two bacterial thiols, MSH and EGT, has a constructive role in the biosynthesis of lincomycin A, a sulfur-containing lincosamide (C8 sugar) antibiotic that has been widely used for half a century to treat Gram-positive bacterial infections6, 7, 8, 9. EGT acts as a carrier to template the molecular assembly, and MSH is the sulfur donor for lincomycin maturation after thiol exchange. These thiols function through two unusual S-glycosylations that program lincosamide transfer, activation and modification, providing the first paradigm for EGT-associated biochemical processes and for the poorly understood MSH-dependent biotransformations, a newly described model that is potentially common in the incorporation of sulfur, an element essential for life and ubiquitous in living systems.
Winter festivities and celebrations are gaining pace in the national Capital, where the stage is set for families to dive into the festive celebrations and to enjoy to their heart’s content.In a bid to boost tourism in the city, Delhi Tourism is organising ‘Winter Carnival’ from December 18-27 at Dilli Haat, INA and ‘X-Mas Carnival’ from December 25-27 at Dilli Haat, Janak Puri. To mark the beginning of the festive season, guests and visitors can look forward to a unique Christmas bazaar at both Dilli Haats, which is the main attraction and in order to build up the excitement, Santa Claus would be moving around the venue distributing candies to charm the little ones. To create a unique atmosphere, Church of Delhi would conduct singing of Christmas carols and cultural programmes every evening in order to light up the mood of the visitors. Dilli Haat Janakpuri will organise various other events like camel rides, joy rides, food delicacies of other states, cakes and chocolate stalls, adventure parks and handloom and handicraft stalls.
New-born babies should be put to bed in the same bedroom as their parents but not on the same bed for the first year of their life. They should be laid on a separate surface or a crib as this may help avoid cot death among infants, researchers have suggested.“Parents should never place the baby on a sofa, couch, or cushioned chair, either alone or sleeping with another person. These surfaces are extremely hazardous,” said lead author Rachel Moon from the University of Virginia in the US. Also Read – Add new books to your shelfSudden infant death syndrome (SIDS), also known as cot death or crib death, is the sudden unexplained death of a child less than one year of age. “We know that parents may be overwhelmed with a new baby in the home, and we want to provide them with clear and simple guidance on how and where to put their infant to sleep,” Moon added, in a new policy statement released by the American Academy of Pediatrics.Explaining how to create a safe sleep environment for babies, child health experts recommended skin-to-skin care regardless of feeding or delivery method, immediately following birth for at least an hour as soon as the mother is medically stable and awake. Also Read – Over 2 hours screen time daily will make your kids impulsiveWhile infants are at heightened risk for SIDS between the ages one and four months, new evidence shows that soft bedding continues to pose hazards to babies who are four months and older.Thus, after feeding, parents should move the baby to his or her separate sleeping space, preferably a crib or bassinet in the parents’ bedroom. “There should be no pillows, sheets, blankets or other items that could obstruct the infant’s breathing or cause overheating,” noted Lori Feldman-Winter, Professor at Cooper University Hospital in New Jersey, US. “If you are feeding your baby and think that there’s even the slightest possibility that you may fall asleep, feed your baby on your bed, rather than a sofa or cushioned chair,” Feldman-Winter suggested in the report published online in the journal Pediatrics.